RELATIONSHIP BETWEEN CEREBRAL ARTERY BLOOD FLOW VELOCITIES AND SICKLE CELL SEVERITY
Author(s): Ezeuko L. C.; Odunvbun M. E.; Ikejiaku U. P.; Ike I. I.; Anthony-Eweputanna S. A.; Ezerioha O. P.; Ezeuko V. C.; Onwumere U. O.
Institute(s): 1,3,4,5,6 Department of Paediatrics, FUTH, Owerri; 2 Department of Child Health, UBTH, Benin City; 7 Department of Anatomy, UNIBEN, Benin City; 8 Department of Paediatrics, NAUTH
Volume 7 / Issue 2
Abstract
Sickle Cell Anaemia (SCA) is a chronic haemolytic state associated with recurrent blood transfusions, infections, and its attendant complications. Vasocclusion results in the narrowing of the major cerebral blood vessel which predisposes children with SCA to the development of multisystem complications. Cerebral blood flow velocity can be assessed using transcranial doppler ultrasound and the sickle cell disease severity can be assessed using a scoring system by Adegoke and Kuti adopted for use in Nigeria for disease severity. The study compared the relationship between cerebral artery blood flow velocities (CBFV) and sickle cell disease severity in SCA children aged 2-16 years seen at Federal Teaching Hospital Owerri, Imo state.
Number of Pages: 7
Number of Words: 3282
First Page: 55
Last Page: 62